Naloxone

Drug Status in USA : Approved
Drug Status in Canada : Approved

Indication : Why is this medication prescribed?

Specific antidote to morphine. For reversing neonatal asphyxia due to opioid use during labor. To reverse respiratory depression due to intraoperative use of opioids. Adjunct to intraspinal opioid analgesia. Alcohol intoxication. Naloxone has been found to elevate BP in endotoxic or hypovolaemic shock, stroke and spinal injury.

Contraindication: What are the special precautions to be followed?

Under following conditions, use of this medication is inadvisable. Its use should be withhold as it would cause harm to the patient
Hypersensitivity.

Other Precaution to be observed while taking this medication

Hypertension. Pregnancy and lactation.

What are possible side effects of this medication ?

Nausea, vomiting, extreme hypertension (after large therapeutic dose of opioids and in addicts). Ventricular tachycardia and fibrillation, dyspnoea, pulmonary oedema. Recurrence of resp depression in LA opioids.

Drug Category/Class

  • Antidotes
  • Cytochrome P-450 CYP2C8 Inhibitors
  • Cytochrome P-450 CYP2C8 Inducers
  • CYP3A4 Inhibitors
  • Narcotic Antagonists
  • Central Nervous System Depressants
  • Antidotes
Prescribed For the complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids including natural and synthetic n...
Weight :327.3743
Structure Naloxone
Generic Drug Naloxone prescribed For the complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids including natural and synthetic n...
Formula

C19H21NO4

Naloxone has 5 Brands listed


Nalox (400 mcg)Narcotan (40 mcg)
Narcotan (400 mcg)Nex (40 mcg)
Nex (400 mcg)

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