Drug Status in USA : Approved Drug Status in Canada : Approved
Indication : Why is this medication prescribed?
Imipenem is always available in combination with Cilastatin. It is an extremely potent against broad-spectrum beta-lactam antibiotic whose range of activity includes gram positive cocci, Enterobacteriaceae, Ps aeruginosa, Listeria as well as anaerobes like Bact.fragilis and Cl. difficile. It is also effective in a wide range of serious hospital acquired infections including those in neutropenic, cancer and AIDS patients.
Contraindication: What are the special precautions to be followed?
Under following conditions, use of this medication is inadvisable. Its use should be withhold as it would cause harm to the patient Hypersensitivity.
Other Precaution to be observed while taking this medication
Potential risk to the foetus. CNS disorders such as epilepsy, renal, hepatic impairment. Pregnancy and lactation. In patients having history of convulsions, the drug should not be started before starting anti-convulsant therapy.
What are possible side effects of this medication ?
Skin rashes, urticaria, eosinophilia, fever, nausea, vomiting, diarrhoea, tooth or tongue discoloration and altered taste. It induce seizures at higher doses.
Drug Category/Class
Carbapenems
Anti-Bacterial Agents
Antibacterials for Systemic Use
Antiinfectives for Systemic Use
Carbapenems
Prescribed
For the treatment of bacterial infections caused by susceptible bacteria.