Fosphenytoin
Drug Status in USA : Approved
Drug Status in Canada : Approved
Indication : Why is this medication prescribed?
Status epilepticus prevention and treatment of seizures during neurosurgery.
Contraindication: What are the special precautions to be followed?
Under following conditions, use of this medication is inadvisable. Its use should be withhold as it would cause harm to the patient
Porphyria, sinus bradycardia, SA block, 2nd and 3rd degree heart block. Stokes-Adams syndrome. Pregnancy and lactation.Other Precaution to be observed while taking this medication
Hepatic or renal impairment, hypoalbuminaemia, elderly patients, requiring phosphate restriction, resuscitation facilities must be available. Monitor ECG, BP and resp function during infusion.
What are possible side effects of this medication ?
Burning, itching and paraesthesia in the groin area following IV admin, asystole, ventricular fibrillation, hypotension, bradycardia, heart block. Severe CV reactions.
Drug Category/Class
- Antiepileptics
- Hydantoin Derivatives
- Anticonvulsants
- Nervous System
- Cytochrome P-450 CYP2B6 Inducers
- Cytochrome P-450 CYP2B6 Inhibitors
- CYP2B6 Inhibitors (strong)
- Cytochrome P-450 CYP2C9 Inhibitors
- Cytochrome P-450 CYP2C8 Inhibitors
- Cytochrome P-450 CYP2C9 Inducers
- Cytochrome P-450 CYP2C19 Inducers
- Cytochrome P-450 CYP2C8 Inducers
- CYP3A4 Inhibitors
- Hydantoin derivatives
| Prescribed | For the control of generalized convulsive status epilepticus and prevention and treatment of seizures occurring during neurosurgery. It can also be... |
| Weight : | 362.2739 |
| Structure | Fosphenytoin |
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| Formula | C16H15N2O6P |
Fosphenytoin has 5 Brands listed
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