Prothionamide

Indication : Why is this medication prescribed?

Second line anti-tubercular drug.

Contraindication: What are the special precautions to be followed?

Under following conditions, use of this medication is inadvisable. Its use should be withhold as it would cause harm to the patient
Hypersensitivity, severe liver disease, porphyria.

Other Precaution to be observed while taking this medication

Difficulty in managing DM. Monitor blood glucose, thyroid and visual function. Perform LFT before and during treatment. Caution in patients with psychiatric illness or depression. Pregnancy and lactation.

What are possible side effects of this medication ?

Anorexia, nausea and vomiting, metalic taste, abdominal pain, diarrhoea, severe postural hypotension, mental depression and drowsiness, blurred vision, olfactory disturbances (alterations in smell), dizziness, headache, restlessness and tremors. Peripheral and/or optic neuritis, psychiatric disturbances, e.g. depression, anxiety, psychosis, postural hypotension. Jaundice, hepatitis. Thrombocytopenia, skin rashes, stomatitis.

Drug Category/Class

Prothionamide has 9 Brands listed


MD Pride (250 mg)Mdpride (250 mg)
Mycotuf P (250 mg)Pethide (250 mg)
Prabcox 250Prothicid (250 mg)
Prothiocid (250 mg)Protokox FC (250 mg)
Protomid (250 mg)

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