Drug Status in USA : Approved
Drug Status in Canada : Approved


pronounced as (proe jes' ter one)

Why is this medication prescribed?

Progesterone is used as a part of hormone replacement therapy in women who have passed menopause (the change of life) and have not had a hysterectomy (surgery to remove the uterus). Hormone replacement therapy usually includes estrogen, which is used to treat symptoms of menopause and reduce the risk of developing certain diseases. However, estrogen can also cause abnormal thickening of the lining of the uterus and increase the risk of developing uterine cancer. Progesterone helps to prevent this thickening and decreases the risk of developing uterine cancer. Progesterone is also used to bring on menstruation (period) in women of childbearing age who have had normal periods and then stopped menstruating. Progesterone is in a class of medications called progestins (female hormones). It works as part of hormone replacement therapy by decreasing the amount of estrogen in the uterus. It works to bring on menstruation by replacing the natural progesterone that some women are missing.

How should this medicine be used?

Progesterone comes as a capsule to take by mouth. It is usually taken once a day in the evening or at bedtime. You will probably take progesterone on a rotating schedule that alternates 10 to 12 days when you take progesterone with 16 to 18 days when you do not take the medication. Your doctor will tell you exactly when to take progesterone. To help you remember to take progesterone, take it around the same time in the evening. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take progesterone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Continue to take progesterone as directed even if you feel well. Do not stop taking progesterone without talking to your doctor.

What are the precautions to be followed?

Before taking progesterone,
  • tell your doctor and pharmacist if you are allergic to progesterone, oral contraceptives (birth control pills), hormone replacement therapy, any other medications, or peanuts.
  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking. Be sure to mention any of the following: amiodarone (Cordarone, Pacerone); antifungals such as fluconazole (Diflucan), itraconazole (Sporanox), and ketoconazole (Nizoral); cimetidine (Tagamet); clarithromycin (Biaxin); cyclosporine (Neoral, Samdimmune); danazol (Danocrine); delaviridine (Rescriptor); diltiazem (Cardizem, Dilacor, Tiazac); erythromycin (E.E.S, E-Mycin, Erythrocin); fluoxetine (Prozac, Sarafem); fluvoxamine (Luvox); HIV protease inhibitors such as indinavir (Crixivan), ritonavir (Norvir), and saquinavir (Fortovase); isoniazid (INH, Nydrazid); lansoprazole (Prevacid, Prevpac); metronidazole (Flagyl); nefazodone (Serzone); omeprazole (Prilosec); oral contraceptives (birth control pills); ticlopidine (Ticlid); troleandomycin (TAO); verapamil (Calan, Covera, Isoptin, Verelan); and zafirlukast (Accolate). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor what herbal products you are taking, especially St. John's wort.
  • tell your doctor if you have or have ever had unexplained vaginal bleeding between periods; a miscarriage in which some tissue was left in the uterus; cancer of the breasts or female organs; seizures; migraine headaches; asthma; diabetes; depression; blood clots in the legs, lungs, eyes, brain, or anywhere in the body; stroke or ministroke; vision problems; or liver, kidney, heart, or gallbladder disease .
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking progesterone, call your doctor.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking progesterone.
  • you should know that progesterone may make you dizzy or drowsy. Do not drive a car or operate machinery until you know how this medication affects you. If progesterone does make you dizzy or drowsy, take your daily dose at bedtime.
  • you should know that progesterone may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. This is more common when you first start taking progesterone. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.

What are possible side effects of this medication ?

Progesterone may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
  • headache
  • breast tenderness or pain
  • upset stomach
  • vomiting
  • diarrhea
  • constipation
  • tiredness
  • muscle, joint, or bone pain
  • mood swings
  • irritability
  • excessive worrying
  • runny nose
  • sneezing
  • cough
  • vaginal discharge
  • problems urinating
Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:
  • breast lumps
  • migraine headache
  • severe dizziness or faintness
  • slow or difficult speech
  • weakness or numbness of an arm or leg
  • lack of coordination or loss of balance
  • shortness of breath
  • fast heartbeat
  • sharp chest pain
  • coughing up blood
  • leg swelling or pain
  • loss of vision or blurred vision
  • bulging eyes
  • double vision
  • unexpected vaginal bleeding
  • shaking hands that you cannot control
  • seizures
  • stomach pain or swelling
  • depression
  • hives
  • skin rash
  • itching
  • difficulty breathing or swallowing
  • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
  • hoarseness

Laboratory animals who were given progesterone developed tumors. It is not known if progesterone increases the risk of tumors in humans. Talk to your doctor about the risks of taking this medication.

Medications like progesterone may cause abnormal blood clotting. This may cut off the blood supply to the brain, heart, lungs, or eyes and cause serious problems. Call your doctor if you experience any of the symptoms listed above as serious side effects. Talk to your doctor about the risks of taking this medication.

Progesterone may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

How to store the medication and dispose it of after its use later?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program.

Drug Category/Class

  • Progestins
  • Contraceptive Agents
  • Progestogens
  • Pregnen (4) Derivatives
  • BSEP
  • ABCB11 Inhibitors
  • Combined Inducers of CYP3A4 and P-glycoprotein
  • CYP2A6 Inhibitors
  • CYP2A6 Inhibitors (strong)
  • CYP2A6 Inhibitors (moderate)
  • CYP2A6 Inducers
  • CYP2A6 Inducers (strong)
  • Cytochrome P-450 CYP1A2 Inhibitors
  • Cytochrome P-450 CYP1A2 Inducers
  • CYP2D6 Inducers
  • CYP2D6 Inducers (strong)
  • Sex Hor
Prescribed For progesterone supplementation or replacement as part of an Assisted Reproductive Technology (ART) treatment for infertile women with progesteron...
Weight :314.4617
Structure Progesterone
Generic Drug Progesterone prescribed For progesterone supplementation or replacement as part of an Assisted Reproductive Technology (ART) treatment for infertile women with progesteron...


Progesterone has 278 Brands listed

Algest (100 mg)Algest (200 mg)
Algest Inj (200 mg)Anigest (200 mg)
Argest (100 mg)Argest (200 mg)
Argest Cap (100 mg)Argest Cap (200 mg)
Arigest (100 mg)Arigest Inj (100 mg)
Arigest Inj (200 mg)Arigest SG (200 mg)
Awnagest (100 mg)C Hop (100 mg)
C Hop (200 mg)C Hop (300 mg)
C Hop (400 mg)Cap Voranin SG (100 mg)
Cap Voranin SG (200 mg)Conest (100 mg)
Conest (200 mg)Conest (300 mg)
Conest (400 mg)Corion NP (100 mg)
Corion NP (200 mg)Cygest (100 mg)
Cygest (200 mg)Cygest (400 mg)
Deltron (100 mg)Deltron Inj (200 mg)
Deltron SG (200 mg)Dubagest (100 mg)
Dubagest (200 mg)Durogest (100 mg)
Durogest (200 mg)Durogest (200 mg)
E Gest (100 mg)E Gest (200 mg)
Egeria (100 mg)Egeria (200 mg)
Endogest (100 mg)Endogest (200 mg)
Endogest (300 mg)ETS (100 mg)
ETS (200 mg)ETS (400 mg)
ETS Inj (100 mg)ETS Inj (200 mg)
Even (100 mg)Even (200 mg)
Ferliter (100 mg)Firm Up (100 mg)
Firm Up (200 mg)FM Gest
Forgest (100 mg)Forgest Inj (200 mg)
Forgest SG (100 mg)Forgest SG (200 mg)
Fulgest (100 mg)Fulgest (200 mg)
Gemgest (100 mg)Genegest (200 mg)
Ges One (100 mg)Ges One (200 mg)
Ges One Inj (100 mg)Ges One Inj (200 mg)
Gestafine (200 mg)Gestasure (200 mg)
Gestel (100 mg)Gestel (200 mg)
Gester NP (100 mg)Gester NP (200 mg)
Gester NP Inj (100 mg)Gestmate (200 mg)
Gestofit (50 mg) (Ind-Swift)Gestone (100 mg)
Gestone (200 mg)Gestone (50 mg)
Gestone Inj (100 mg)Gestorin (100 mg)
Gestorin (200 mg)Gestorin Inj (100 mg)
Gestorin Inj (200 mg)Gestovin (100 mg)
Gestovin (200 mg)Gravion (200 mg)
Gynogest N (100 mg)Gynogest N (200 mg)
Hald (200 mg)Hema (100 mg)
Hema (200 mg)Hema SG (100 mg)
Hema SG (200 mg)Her NMP (100 mg)
Her NMP (200 mg)Hormorin (100 mg)
Hormorin (200 mg)Inj Voranin (100 mg)
Inj Voranin (200 mg)Inj Voranin (50 mg)
Inogest (100 mg)Inogest (200 mg)
Joprest (100 mg)Joprest (200 mg)
K Preg (100 mg)K Preg (200 mg)
Kreate (100 mg)Kreate (200 mg)
LGP (100 mg)LGP (200 mg)
Lupigest (100 mg)Lupigest (200 mg)
Lupigest (300 mg)Lutacare (100 mg)
Lutacare (200 mg)Lutacare Inj (100 mg)
Lutacare Inj (200 mg)Maa N (100 mg)
Maa N (200 mg)Macgest (100 mg)
Macgest (200 mg)Menoxy N (100 mg)
Menoxy N (200 mg)Menoxy N Inj (200 mg)
Merigest (100 mg)Merigest (200 mg)
Merigest Inj (100 mg)Merigest Inj (200 mg)
Micpro (100 mg)Micpro (200 mg)
Micpro (400 mg)Micpro Inj (100 mg)
Micpro Inj (200 mg)Micpro Inj (50 mg)
Microgest (100 mg)Microgest (200 mg)
Microgest (400 mg)Micronat (200 mg)
Micronat Inj (200 mg)Microprogesta (100 mg)
Minagest (100 mg)Minagest (200 mg)
Minagest TM (100 mg)Minagest TM (200 mg)
Miprogen (Vaginal) (100 mg)Miprogen (Vaginal) (200 mg)
Miprogen (Vaginal) (400 mg)Miprogen Inj (100 mg)
Miprogen Inj (200 mg)Miprogen Inj (50 mg)
Nam (100 mg) (Progestrone)Nam (200 mg) (Progestrone))
Natpreg (200 mg)Natron (100 mg)
Natron (30 ml)Naturogest Inj (100 mg)
Naturogest Inj (200 mg)Naturone (100 mg)
Naturone (200 mg)Naturone Inj (100 mg)
Naturone Inj (200 mg)Neogest (100 mg)
Neogest (200 mg)Neogest (300 mg)
Neogest (400 mg)Neogest Inj (100 mg)
Neogest Inj (50 mg)Nidagen (100 mg)
Nidagen (200 mg)NT Natal MP (100 mg)
NT Natal MP (200 mg)Nujest 100
Nujest 200Ogest (100 mg)
Ogest (200 mg)Onastrone (100 mg)
OptogestOrgagest (100 mg)
Orgagest (200 mg)Orgasest (100 mg)
Orgasest (200 mg)Ornapro (100 mg)
Ornapro (100 mg) (Soft Pharma)Ornapro (200 mg)
Ornapro Inj (200 mg)P4 SR
Pee Tone (250 mg)Pee Tone (500 mg)
Peritone (200 mg)Pgfast
Precare (100 mg)Precare (200 mg)
Pregat (250 mg)Pregat (500 mg)
Pregcitil (100 mg)Pregcitil (200 mg)
Preglon (100 mg)Preglon (200 mg)
Preglon Inj (200 mg)Pregtain (100 mg)
Pregtain (200 mg)Pregzed (250 mg)
Pro One (100 mg)Pro One (200 mg)
Pro One Inj (100 mg)Pro One Inj (200 mg)
Profine (100 mg)Profine (200 mg)
Profine Inj (100 mg)Proge One (100 mg)
Proge One (200 mg)Progest (100 mg) (Multicure)
Progest (200 mg) (Multicure Labs)Progez (100 mg)
Progminat (100 mg)Progminat (200 mg)
Promyzz DS (200 mg)Propeg (100 mg)
Propeg (200 mg)Propeg Inj (100 mg)
Propeg Inj (200 mg)Proza N (100 mg)
Prozy (200 mg)Pyrtex (100 mg)
Pyrtex (200 mg)Pyrtex Inj (100 mg)
Pyrtex Inj (200 mg)Remens (200 mg)
Remens Inj (100 mg)Remens Inj (200 mg)
Rhogest (100 mg)Rhogest (200 mg)
Rivgest (100 mg)Rivgest (200 mg)
Rivgest M (10 mg)Sayopreg (250 mg)
Sayopreg (500 mg)Sofia (100 mg)
Sofia (200 mg)Softgest (200 mg)
Sperogest (100 mg)Strone (100 mg)
Strone (50 mg)Sugest (100 mg)
Sugest (200 mg)Sugest SG (100 mg)
Sugest SG (200 mg)Sugest SG (400 mg)
Sugesterone (100 mg)Sugesterone (200 mg)
Susten (400 mg)Susten Gel (1 gm)
Susten Inj (100 mg)Susten Inj (200 mg)
Sygest (100 mg)Sygest (200 mg)
Truegest (100 mg)Uniprogestin (50 mg)
Uterone (100 mg)Uterone (200 mg)
Uterone (50 mg)Uterone Inj (100 mg)
Vageston (100 mg)Vageston (200 mg)
Vageston (400 mg)Voranin (100 mg)
Voranin (200 mg)Voranin Inj (100 mg)
Wisrone (200 mg)Wisrone Softgel (100 mg)
Xtracare (100 mg)Xtracare (200 mg)
Zesty (100 mg)Zoygest (200 mg)
Zygogest (100 mg)Zygogest (200 mg)
Zystrone (100 mg)Zystrone Inj (100 mg)

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