Ondansetron

Drug Status in USA : Approved
Drug Status in Canada : Approved

pronunciation

pronounced as (on dan' se tron)

Why is this medication prescribed?

Ondansetron is used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, and surgery. Ondansetron is in a class of medications called serotonin 5-HT3 receptor antagonists. It works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting.


How should this medicine be used?

Ondansetron comes as a tablet, a rapidly disintegrating (dissolving) tablet, and an oral solution (liquid) to take by mouth. The first dose of ondansetron is usually taken 30 minutes before the start of chemotherapy, 1 to 2 hours before the start of radiation therapy, or 1 hour before surgery. Additional doses are sometimes taken one to three times a day during chemotherapy or radiation therapy and for 1 to 2 days after the end of treatment. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take ondansetron exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

If you are taking the rapidly disintegrating tablet, remove the tablet from the package just before you take your dose. To open the package, do not try to push the tablet through the foil backing of the blister. Instead, use dry hands to peel back the foil backing. Gently remove the tablet and immediately place the tablet on the top of your tongue. The tablet will dissolve in a few seconds and can be swallowed with saliva.


What are the precautions to be followed?

Before taking ondansetron,
  • tell your doctor and pharmacist if you are allergic to ondansetron, alosetron (Lotronex), dolasetron (Anzemet), granisetron (Kytril), palonosetron (Aloxi, in Akynzeo), any other medications, or any of the ingredients in ondansetron tablets or liquid. Ask your pharmacist for a list of the ingredients.
  • tell your doctor if you are receiving apomorphine (Apokyn). Your doctor will probably tell you not to take ondansetron if you are receiving this medication.
  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: certain medications for seizures such as carbamazepine (Carbatrol, Epitol, Equetro, Tegretol) or phenytoin (Dilantin); clarithromycin (Biaxin, in Prevpac); erythromycin (E.E.S., Erythrocin, others); fentanyl (Abstral, Actiq, Duragesic, Fentora, Lazanda, Onsolis, Subsys); lithium (Lithobid); medications for irregular heart beat; medications for mental illness; medications to treat migraines such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), and zolmitriptan (Zomig); methylene blue; mirtazapine (Remeron); monoamine oxidase (MAO) inhibitors including isocarboxazid (Marplan), linezolid (Zyvox), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate); moxifloxacin (Avelox); selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, in Symbyax), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), and sertraline (Zoloft); and tramadol (Conzip, Ultram, in Ultracet). Your doctor may need to change the doses of your medications or monitor you more carefully for side effects. Many other medications may also interact with ondansetron, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
  • tell your doctor if you or anyone in your family has or has ever had long QT syndrome (condition that increases the risk of developing an irregular heartbeat that may cause fainting or sudden death), or another type of irregular heart beat or heart rhythm problem, or if you have or have ever had low blood levels of magnesium or potassium in your blood, heart failure (HF; condition in which the heart cannot pump enough blood to other parts of the body), or liver disease.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking ondansetron, call your doctor.
  • if you have phenylketonuria (PKU, an inherited condition in which a special diet must be followed to prevent mental retardation), you should know that the orally disintegrating tablets contain aspartame that forms phenylalanine.

What are possible side effects of this medication ?

Ondansetron may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
  • headache
  • constipation
  • weakness
  • tiredness
  • chills
  • drowsiness
Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately or seek emergency medical treatment:
  • blurred vision or vision loss
  • rash
  • hives
  • itching
  • swelling of the eyes, face, lips, tongue, throat, hands, feet, ankles, or lower legs
  • hoarseness
  • difficulty breathing or swallowing
  • chest pain
  • shortness of breath
  • dizziness, light-headedness, or fainting
  • fast, slow or irregular heartbeat
  • agitation
  • hallucinations (seeing things or hearing voices that do not exist)
  • fever
  • excessive sweating
  • confusion
  • nausea, vomiting, or diarrhea
  • loss of coordination
  • stiff or twitching muscles
  • seizures
  • coma (loss of consciousness)

Ondansetron may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication.


How to store the medication and dispose it of after its use later?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store the tablets and rapidly disintegrating tablets away from light, at room temperature or in the refrigerator. Store the solution in the bottle upright at room temperature and away from light, excess heat, and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program.


Drug Category/Class

  • Anti-Anxiety Agents
  • Antipsychotic Agents
  • Serotonin Antagonists
  • Antipruritics
  • Antiemetics
  • Alimentary Tract and Metabolism
  • Serotonin (5Ht3) Antagonists
  • Antiemetics and Antinauseants
  • Cytochrome P-450 CYP1A2 Inhibitors
  • Cytochrome P-450 CYP2C9 Inhibitors
  • Cytochrome P-450 CYP1A2 Inducers
  • Cytochrome P-450 CYP2C9 Inducers
  • CYP2D6 Inducers
  • CYP2D6 Inducers (strong)
  • CYP2E1 Inhibito
Prescribed For the prevention of nausea and vomiting associated with emetogenic cancer chemotherapy, postoperation, and radiation. Also used for the treatment...
Weight :293.363
Structure Ondansetron
Generic Drug Ondansetron prescribed For the prevention of nausea and vomiting associated with emetogenic cancer chemotherapy, postoperation, and radiation. Also used for the treatment...
Formula

C18H19N3O

Ondansetron has 661 Brands listed


5HT3A MD (30 ml)5HT3A MD (4 mg)
5HT3A MD Inj (4 mg)A Tron (4 mg)
A Tron MD (4 mg)Abyrone (4 mg)
Adom O (4 mg)Aerodol (4 mg)
Afon MD (4 mg)Alset (30 ml)
Alset (4 mg)Amvtron DT (4 mg)
Anset (15 ml)Anset (30 ml)
Anset (4 mg)Anset (8 mg)
Anset Inj (4 mg)Anset MD (4 mg)
Anset Tab (8 mg)Antron (30 ml)
Antron (4 mg)Aridone (30 ml)
Avomits (30 ml)Avomits (4 mg)
Awnaron (4 mg)Axiset (2 mg)
Axiset (30 ml)Axiset (4 mg)
B DON MD4Back2norm (4 mg)
Back2norm (8 mg)Bisetron (4 mg)
Bludan (2 mg)Bludan (30 ml)
Bludan MD (4 mg)Bludan MD (8 mg)
Bond (4 mg)Bond Tab (4 mg)
Chew IT (4 mg)Chiset O (8 mg)
Corlon (4 mg)Danee (30 ml)
Danee (4 mg)Danset (4 mg)
Danset (8 mg)Dasin (2 mg)
Dense (2 mg)Dense (30 ml)
Dense (4 mg)Dentron (4 mg)
Doin 4 mg)Domi Up (30 ml)
Domi UP (4 mg)Domi UP (8 mg)
Domi UP Inj (4 mg)Domlet (4 mg)
Domlet (60 ml)Donif (30 ml)
Donif (4 mg)Donset (4 mg)
Donset (8 mg)Donset Inj (4 mg)
Donset Inj (8 mg)Doran O (4 mg)
Dotson (4 mg)Dotson MD (4 mg)
Dutron (30 ml)E ON (4 mg)
Emeban (2 mg)Emeban (4 mg)
Emeban (8 mg)Emefilm 2
Emekule (30 ml)Emekule MD (4 mg)
Emeram O (5 ml)Emeram O (8 mg)
Emeran (4 mg)Emeran (8 mg)
Emeran Inj (4 mg)Emeran Inj (8 mg)
Emerest (2 mg)Emerest (30 ml)
Emerest (4 mg)Emerest (8 mg)
Emeril (2 mg)Emeril (30 ml)
Emeril (4 mg)Emesafe (4 mg)
Emeset (30 ml)Emeset (4 mg)
Emeset (8 mg)Emeset Inj (4 mg)
Emeset Inj (8 mg)Emestal O (30 ml)
Emestal O (4 mg)Emesys (4 mg)
Emesys (8 mg)Emetek (20 mg)
Emetek (30 ml)Emetek MD (4 mg)
Emetop (30 ml)Emigo (30 ml)
Emigo (4 mg)Emigo (8 mg)
Emigo MD (4 mg)Emigo Tab (4 mg)
Emigo Tab (8 mg)Emitino (30 ml)
Emitino (4 mg)Emitron (4 mg)
Emitron (8 mg)Emitron Inj (4 mg)
Emitron Inj (8 mg)Emitus (30 ml)
Emitus (4 mg)Emitus MD (4 mg)
Emnil (30 ml)Emnil (4 mg)
Emnil (8 mg)Emnil MD (4 mg)
Emsetron (4 mg)Emsetron (8 mg)
Emsetron Inj (4 mg)Emsetron Inj (8 mg)
Emtron (30 ml)Emtron (4 mg)
Emtron (8 mg)Emtron MD (4 mg)
Entil (4 mg)Estil MD (4 mg)
F Lexi (4 mg)Flatron (2 mg)
Flatron (30 ml)Flatron (4 mg)
Flexi (30 ml)Flexi (4 mg)
Flexi Tab (4 mg)Glendan (30 ml)
Glendan (4 mg)Hexaon (4 mg)
Higo (4 mg)Higo (8 mg)
Higo MDHigo Solution
Hitch (4 mg)Hitch (8 mg)
K Tron (30 ml)K Tron (4 mg)
K Tron (8 mg)K Tron Inj (4 mg)
Kanset (2 mg)Kanset (30 ml)
Kanset (4 mg)Kapitron
Kenset (4 mg)Kidon (30 ml)
Kidon (4 mg)Kidon (8 mg)
Kindon (30 ml)Kloset (4 mg)
Levom (4 mg)Lupisetron (8 mg)
Lupisetron Ini (4 mg)Lupisetron Tab (4 mg)
LuxitronMeddy (2 mg)
Meristron (2 mg)Meristron (4 mg)
Monda (4 mg)MP Nova (2 mg)
MP Nova (30 ml)MP Nova (4 mg)
Munset MD (4 mg)Mytic (30 ml)
Mytic (4 mg)Mytic MD (4 mg)
Naucid (20 mg)Naucid (30 ml)
Naucid (4 mg)Naucid Inj (4 mg)
Nauset (2 mg)Nauset (30 ml)
Nauset MDNeomit (4 mg)
Neomit (8 mg)Neomit Inj (4 mg)
Neomit Inj (8 mg)Nitron (4 mg)
Nolti (30 ml)Novatron (30 ml)
Novatron (4 mg)Novomit (4 mg)
Novomit Inj (10 mg)Novon (2 mg)
Novon (30 ml)Novon (4 mg)
Nuset (4 mg)Nuset (8 mg)
Nvnil (4 mg)Nvset DT
NvsetronNvsetron (4 mg)
Oare ON (4 mg)Oblong (2 mg)
Odanse (30 ml)Odanse FC (4 mg)
Odean (30 ml)Odean (4 mg)
Odean InjOdep (4 mg)
Odep Tab (4 mg)Odestron (4 mg)
ODN (30 ml)ODN (4 mg)
Odonet (4 mg)Odonet Inj (4 mg)
Omcet (30 ml)Omcet (4 mg)
Ometic (2 mg)Ometic (30 ml)
Ometic DT (2 mg)Ometic MD (4 mg)
Ominil (4 mg)Omit (4 mg)
Omit (8 mg)Omitron (2 mg)
ON J (2 mg)On N On (4 mg)
Onandes (30 ml)Oncare (4 mg)
Oncoden (4 mg)Oncoden (8 mg)
Oncoden Inj (4 mg)Oncoden Inj (8 mg)
Ond (30 ml)Ond (4 mg)
Ond Inj (4 mg)Onda (4 mg)
Ondace (2 mg)Ondace (30 ml)
Ondace MD (4 mg)Ondacon (4 mg)
Ondader (30 ml)Ondader (4 mg)
Ondader (8 mg)Ondader Inj (4 mg)
Ondai (2 mg)Ondai (30 ml)
Ondai (4 mg)Ondai (8 mg)
Ondamac (4 mg)Ondansetran (2 mg)
Ondansetron (4 mg)Ondansetron 2 mg ml (Jan Aushadhi)
Ondansetron 4 mg (Jan Aushadhi)Ondanz (30 ml)
Ondanz (4 mg)Ondanz (8 mg)
Ondanz DT (4 mg)Ondanz DT (8 mg)
Ondap (30 ml)Ondap (4 mg)
Ondar (4 mg)Ondar Tab (4 mg)
Ondarom (30 ml)Ondarom (4 mg)
Ondarom (8 mg)Ondarom Tab (4 mg)
Ondas (4 mg)Ondavom (4 mg)
Ondavom (4 mg) (Acron Labs)Ondavom (4 mg) (Acron Pharma)
Ondavom (8 mg)Ondavom Inj (4 mg)
Ondavom Inj (8 mg)Ondax (30 ml)
Ondax (4 mg)Ondaz (30 ml)
Ondee (4 mg)Ondem (4 mg)
Ondem (8 mg)Ondem Inj (4 mg)
Ondem Inj (8 mg)Ondem MD (4 mg)
Ondem MD (8 mg)Ondenat
OnderonOnderon (30 ml)
Onderon DT (4 mg)Ondet (30 ml)
Ondet (30 ml) (Intas Labs)Ondet (4 mg)
Ondet (4 mg) (Neuron Pharma)Ondet (8 mg)
Ondet Inj (20 mg)Ondet Inj (4 mg)
Ondet Tab (4 mg)Ondex (30 ml)
Ondex (4 mg)Ondigo (30 ml)
Ondigo (4 mg)Ondiwel (4 mg)
Ondix (2 mg)Ondix (4 mg)
Ondix (8 mg)Ondocos (4 mg)
Ondocos (8 mg)Ondocos Inj
Ondogat (2 mg)Ondon (4 mg)
Ondon (8 mg)Ondorise (16 mg)
Ondorise (30 ml)Ondorise Inj (4 mg)
Ondorise Tab (4 mg)Ondosym
Ondosym 4Ondosym Inj
Ondot (30 ml)Ondot (4 mg) (Haledew)
Ondot Inj (4 mg)Ondot MD (4 mg)
Ondralac (4 mg)Ondron (2 mg)
Ondron (4 mg)Ondus MD 8
Ondy (30 ml)Ondy (4 mg)
Oneden (30 ml)Oneeda (30 ml)
Onest (30 ml)Onest (4 mg)
Onest Forte (8 mg)Onest Inj (4 mg)
Onex (4 mg)Onful MD
Ongone (4 mg)Ongone (4 mg)
Ongrace (2 mg)Onkam (2 mg)
Onkam (4 mg)Onkam (8 mg)
Onlit (30 ml)Onlit (4 mg)
Ono (4 mg)Ono (4 mg) (Samarth Pharma)
Ono (8 mg)Ono Tab (8 mg)
Onrid MD (4 mg)Onriv (4 mg)
Onriv (8 mg)Onriz (4 mg)
Onron (4 mg)Onron Tab (4 mg)
Onsar (4 mg)Onsar (8 mg)
Onsat (30 ml)Onset (4 mg)
Onset Tab (4 mg)Onsetron (4 mg)
Onsett (4 mg)Onsett (8 mg)
Onsett Inj (4 mg)Onsett Inj (8 mg)
Onstal (4 mg)Onstal (8 mg)
Onstal Forte (8 mg)Onstal Inj (4 mg)
Onstal Tab (4 mg)Onstal Tab (4 mg) (Anthus Pharma)
Onstal Tab (8 mg)Onstar (4 mg)
Onstar (8 mg)Onstar MD (4 mg)
Onstar MD (8 mg)Ontasyn (20 mg)
Ontasyn (30 ml)Ontasyn (4 mg)
Ontic (20 mg)Ontic (30 ml)
Ontic (4 mg)Ontic MD (4 mg)
Ontil (20 mg)Ontil (4 mg)
Ontiz (4 mg)Ontome MD (4 mg)
Ontron (30 ml)Ontron (4 mg)
ONV (4 mg)ONV MD (4 mg)
Onvir (8 mg)Onytil
Onzy (2 mg)Onzy (30 ml)
Onzy MD (4 mg)Oondosym 8
Optus (20 mg)Optus (30 ml)
Optus (4 mg)Optus (8 mg)
Optus MD (4 mg)Optus MD (8 mg)
Oramide (2 mg)Oran (30 ml)
Oran (4 mg)Oran Inj (4 mg)
Ordon (30 ml)Orio DT (4 mg)
Orlon (4 mg)Oset (30 ml)
Oset (4 mg)Osetril (2 mg)
Osetril (30 ml)Osetril (4 mg)
Osetron (4 mg)Osetron (8 mg)
Osetron Inj (4 mg)Osetron Inj (8 mg)
Osett (4 mg)Osett (8 mg)
Ostron (4 mg)P Set (2 mg)
P Tron (30 ml)P Tron (4 mg)
PeptimazPeptimaz
Peridem (4 mg)Periset (4 mg)
Periset (8 mg)Periset Inj (4 mg)
Periset Inj (8 mg)Petron MD (4 mg)
Petron MD Inj (4 mg)Phytic (4 mg)
Prospect (30 ml)Prospect (4 mg)
Prospect (8 mg)Prospect Tab (4 mg)
Prospect Tab (8 mg)Quoden (30 ml)
Quoden (8 mg)R Wanda
R Wanda TabRajonda (4 mg)
Rajonda Inj (4 mg)Raydatron (2 mg)
Raydatron (4 mg)Refvon (30 ml)
Refvon (4 mg)Refvon MD (4 mg)
Reset (30 ml)Reset (4 mg)
Rhonda MDRockond
Romlex (20 mg)Ronda (2 mg)
Santron (4 mg)Santron (8 mg)
Santron Tab (8 mg)Satron (30 ml)
Satron (4 mg)Seizetron (4 mg)
Set NV (2 mg)Set NV (4 mg)
Setcool (30 ml)Setcool DT (4 mg)
Seteron (8 mg)Setin (30 ml)
Setnor (30 ml)Setnorm (30 ml)
Setnorm (4 mg)Seton (2 mg)
Seton (30 ml)Seton MD (4 mg)
Setradon MD (4 mg)Setradon MD Tab (4 mg)
Setrin (30 ml)Setrin (4 mg)
Setro (4 mg)Setro (8 mg)
Setron (4 mg)Setron (8 mg)
Setron Inj (4 mg)Setron Inj (8 mg)
Setrona (2 mg)Setrona (30 ml)
Setrona (4 mg)Si On (30 ml)
Soset (4 mg)Speronden (30 ml)
Speronden MD (4 mg)Stop EM (30 ml)
Stop EM (4 mg)Stopvom (2 mg)
Stopvom MD (4 mg)Supracetron (2 mg)
Supracetron MD (4 mg)SV (30 ml)
SV (8 mg)Sydol LA (20 mg)
Sydol LA (60 mg)Symset (8 mg)
Toroset (30 ml)Ubitset (4 mg)
Udan (2 mg)Udan (30 ml)
Udan MD (4 mg)V Dom (2 mg)
Valfoed (2 mg)Valfoed (4 mg)
Vegas (30 ml)Vegas (4 mg)
Vegas (8 mg)Vegas Inj (4 mg)
Vegas Inj (8 mg)Versetron (4 mg)
Vomena PD (30 ml)Vomic (30 ml)
Vomic (4 mg)Vomicae (2 mg)
Vomicare (4 mg)Vomicon (4 mg)
Vomidan (4 mg)Vomidan (8 mg)
Vomiden (2 mg)Vomidep (4 mg)
Vomidep Inj (4 mg)Vomidot (30 ml)
Vomidot (4 mg)Vomigo (30 ml)
Vomigo (4 mg)Vomigo Tab (4 mg)
Vomigon (30 ml)Vomigon (4 mg)
Vomigon (8 mg)Vomigon Inj (4 mg)
Vomikind (20 mg)Vomikind (30 ml)
Vomikind (4 mg)Vomikind Inj (4 mg)
Vomikind MD (2 mg)Vomikind MD (4 mg)
Vomilynn (4 mg)Vomilynn Inj (4 mg)
Vomimed (2 mg)Vomin (4 mg)
Vominaus O (4 mg)Vomino (4 mg)
Vominux (2 mg)Vominux (30 ml)
Vominux (4 mg)Vomiof (30 ml)
Vomiof (4 mg)Vomiof (8 mg)
Vomiof Inj (4 mg)Vomiof Inj (8 mg)
Vomiout (2 mg)Vomiout (30 ml)
Vomiout (4 mg)Vomipar (30 ml)
Vomipar (4 mg)Vomipar Inj (4 mg)
Vomipra (4 mg)Vomipra (8 mg)
Vomipra MD (4 mg)Vomiquit (30 ml)
Vomiran (30 ml)Vomiran (8 mg)
Vomirest (20 mg)Vomirest (30 ml)
Vomirest (4 mg)Vomirest Inj (4 mg)
Vomirid (2 mg)Vomirid (4 mg)
Vomirid (5 ml)Vomirock MD
Vomis (4 mg)Vomis (8 mg)
Vomis Inj (4 mg)Vomis Inj (8 mg)
Vomiset (4 mg)Vomiset (8 mg)
Vomiset (8 mg) (Redson)Vomiset Inj (4 mg)
Vomiset Inj (8 mg)Vomiset Susp (30 ml)
Vomison (30 ml)Vomison (4 mg)
Vomisoz (4 mg)Vomistan (30 ml)
Vomistan (4 mg)Vomistar (4 mg)
Vomital (6 mg)Vomito (4 mg)
Vomiton (30 ml)Vomitras (30 ml)
Vomitras MD (4 mg)Vomitron
Vomitron (8 mg)Vomitron Drop
Vomitron InjVomitron MD (4 mg)
Vomiven (2 mg)Vomiven (4 mg)
Vomiver (2 mg)Vomiver (30 ml)
Vomiz (4 mg)Vomiz (8 mg)
Vomiz Inj (4 mg)Vomiz Inj (8 mg)
Vomizen (30 ml)Vomizen (4 mg)
Vomizen Inj (4 mg)Vomnu (30 ml)
Vomnu (4 mg)Vomnu Inj (4 mg)
Vomny (30 ml)Vomny (4 mg)
Vomny MD (4 mg)Vomoff
Vomoron (4 mg)Vomset (4 mg)
Vomset (8 mg)Vomteez (30 ml)
Vona (2 mg)Vondtron (2 mg)
Vondtron (4 mg)Vorast (30 ml)
Vorast (8 mg)Vorast Inj (4 mg)
Vorast Inj (8 mg)Vorast Tab (4 mg)
Voron (4 mg)Vstop (30 ml)
Vstop (4 mg)Vstop Inj (4 mg)
Xenater (4 mg)Xenater MD (4 mg)
Zendon (4 mg)Zofer (4 mg)
Zofer (8 mg)Zofer Inj (4 mg)
Zofer Inj (8 mg)Zofer MD (4 mg)
Zomitron MD (4 mg)Zonda (30 ml)
Zonda (4 mg)Zonda DPS (30 ml)
Zonda Inj (4 mg)Zondan (4 mg)
Zondan (8 mg)Zondan Inj (4 mg)
Zondan Inj (8 mg)Zonde (30 ml)
Zonde (4 mg)Zonde (8 mg)
Zonde Tab (4 mg)Zordil (2 mg)
Zordil (30 ml)Zordil (4 mg)
Zyset (2 mg)

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