Ketoprofen

Drug Status in USA : Approved
Drug Status in Canada : Approved

pronunciation

pronounced as (kee toe proe' fen)

Why is this medication prescribed?

Prescription ketoprofen is used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints) and rheumatoid arthritis (arthritis caused by swelling of the lining of the joints). Prescription ketoprofen capsules are also used to relieve pain, including menstrual pain (pain that occurs before or during a menstrual period). Nonprescription ketoprofen is used to relieve minor aches and pain from headaches, menstrual periods, toothaches, the common cold, muscle aches, and backaches, and to reduce fever. Ketoprofen is in a class of medications called NSAIDs. It works by stopping the body's production of a substance that causes pain, fever, and inflammation.


How should this medicine be used?

Prescription ketoprofen comes as a capsule and extended-release (long-acting) capsule to take by mouth. The capsules are usually taken three or four times a day for arthritis or every 6 to 8 hours as needed for pain. The extended-release capsules are usually taken once daily. If you take ketoprofen regularly, take it at around the same times every day.

Nonprescription ketoprofen comes as a tablet to take by mouth. It is usually taken with a full glass of water or other liquid every 4 to 6 hours as needed.

Follow the directions on the package or prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take ketoprofen exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor or written on the label.

Ketoprofen may be taken with food or milk to prevent upset stomach. Your doctor may also recommend that you take ketoprofen with an antacid to reduce stomach upset.

Your doctor may start you on an average dose of prescription ketoprofen and may increase or decrease on your dose depending on how well you respond to the medication and the side effects you experience. Follow these directions carefully.

Stop taking nonprescription ketoprofen and call your doctor if your symptoms get worse, you develop new or unexpected symptoms, the part of your body that was painful becomes red or swollen, your pain lasts for more than 10 days or your fever lasts for more than 3 days.


What are the precautions to be followed?

Before taking ketoprofen,
  • tell your doctor and pharmacist if you are allergic to ketoprofen, aspirin or other NSAIDs such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn), any other medications, or any of the inactive ingredients in ketoprofen capsules or extended release capsules. Ask your pharmacist for a list of the inactive ingredients.
  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), and trandolapril (Mavik); diuretics ('water pills'); lithium (Eskalith, Lithobid); medications for diabetes; methotrexate (Rheumatrex); phenytoin (Dilantin); probenecid (Benemid); and sulfa antibiotics such as sulfisoxazole (Gantrisin) and sulfamethoxazole (in Bactrim, in Septra). Your doctor may need to change the doses of your medications or monitor you more carefully for side effects.
  • tell your doctor if you have or have ever had any of the conditions mentioned in the IMPORTANT WARNING section or asthma, especially if you also have frequent stuffed or runny nose or nasal polyps (swelling of the lining of the nose); swelling of the hands, arms, feet, ankles, or lower legs; or liver or kidney disease.
  • tell your doctor if you are pregnant especially if you are in the last few months of your pregnancy, you plan to become pregnant, or you are breast-feeding. If you become pregnant while taking ketoprofen, call your doctor.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking ketoprofen.

What are possible side effects of this medication ?

Ketoprofen may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
  • constipation
  • diarrhea
  • sores in the mouth
  • headache
  • dizziness
  • nervousness
  • drowsiness
  • difficulty falling asleep or staying asleep
  • ringing in the ears
Some side effects may be serious. If you experience any of the following symptoms or those mentioned in the IMPORTANT WARNING section, call your doctor immediately. Do not take any more ketoprofen until you speak to your doctor.
  • changes in vision
  • unexplained weight gain
  • fever
  • blisters
  • rash
  • itching
  • hives
  • swelling of the eyes, face, lips, tongue, throat, arms, hands, feet, ankles, or lower legs
  • hoarseness
  • difficulty breathing or swallowing
  • excessive tiredness
  • unusual bleeding or bruising
  • lack of energy
  • loss of appetite
  • nausea
  • pain in the upper right part of the stomach
  • flu-like symptoms
  • yellowing of the skin or eyes
  • pale skin
  • fast heartbeat
  • cloudy, discolored, or bloody urine
  • back pain
  • difficult or painful urination

Ketoprofen may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.


How to store the medication and dispose it of after its use later?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.


Drug Category/Class

  • Antiinflammatory Preparations, Non-Steroids for Topical Use
  • Topical Products for Joint and Muscular Pain
  • Propionic Acid Derivatives
  • Cytochrome P-450 CYP2C9 Inhibitors
  • Cytochrome P-450 CYP2C8 Inhibitors
  • Cytochrome P-450 CYP2C9 Inducers
  • Cytochrome P-450 CYP2C8 Inducers
  • Anti-Inflammatory Agents, Non-Steroidal
  • Cyclooxygenase Inhibitors
  • Musculo-Skeletal System
  • Antiinflammatory and A
Prescribed For symptomatic treatment of acute and chronic rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, primary dysmenorrhea and mild to moder...
Weight :254.2806
Structure Ketoprofen
Generic Drug Ketoprofen prescribed For symptomatic treatment of acute and chronic rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, primary dysmenorrhea and mild to moder...
Formula

C16H14O3

Ketoprofen has 14 Brands listed


Ketofen (100 mg)Ketofen (50 mg)
Ketopatch (30 mg)Ketoplast
Ostofen (50 mg)Redufen (50 mg)
Redufen Retard (100 mg)Rhofenid EC (100 mg)
Rhofenid Gel (30 gm)Rhofenid IM (10 mg)
Rhofenid IV (50 mg)Rhofenid SR (200 mg)
Vofane (50 mg)Vofane (8 mg)

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