Irinotecan

Drug Status in USA : Approved
Drug Status in Canada : Approved

Indication : Why is this medication prescribed?

Metastatic carcinoma of the colon or rectum, cancer lung, cervix, ovary.

Contraindication: What are the special precautions to be followed?

Under following conditions, use of this medication is inadvisable. Its use should be withhold as it would cause harm to the patient
Hypersensitivity. Inflammatory bowel diseases, bowel obstruction, severe hepatic impairment. Pregnancy and lactation.

Other Precaution to be observed while taking this medication

Previous pelvic/abdominal irradiation, elderly. Raised plasma-bilirubin concentration, severe myelosuppression.

What are possible side effects of this medication ?

Abdominal discomfort, vomiting, diarrhoea, nausea. Leukopenia, neutropenia, anaemia, haemorrhage. Body pain, asthenia, insomnia, dizziness, thrombocytopenia, lachrymation, miosis, CV toxicity.

Drug Category/Class

  • Antineoplastic Agents, Phytogenic
  • Radiation-Sensitizing Agents
  • Topoisomerase I Inhibitors
  • Prodrugs
  • Cytochrome P-450 CYP2B6 Inhibitors
  • CYP2B6 Inhibitors (strong)
  • Cytochrome P-450 CYP2B6 Inducers
  • Antineoplastic Agents
  • Antineoplastic and Immunomodulating Agents
  • Immunosuppressive Agents
  • CYP3A4 Inhibitors
  • Other antineoplastic agents
Prescribed For the treatment of metastatic colorectal cancer (first-line therapy when administered with 5-fluorouracil and leucovorin). Also used in combinati...
Weight :586.678
Structure Irinotecan
Generic Drug Irinotecan prescribed For the treatment of metastatic colorectal cancer (first-line therapy when administered with 5-fluorouracil and leucovorin). Also used in combinati...
Formula

C33H38N4O6

Irinotecan has 12 Brands listed


Camto (100 mg)Camto (40 mg)
Intensic (100 mg)Intensic (40 mg)
Irinomil (100 mg)Irinomil (40 mg)
Irinores (100 mg)Irinores (40 mg)
Irnocam (100 mg)Irnocam (40 mg)
Torsirin (100 mg)Torsirin (40 mg)

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