Dinoprostone

Drug Status in USA : Approved
Drug Status in Canada : Approved

pronunciation

pronounced as (dye noe prost' one)

Why is this medication prescribed?

Dinoprostone is used to prepare the cervix for the induction of labor in pregnant women who are at or near term. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.


How should this medicine be used?

Dinoprostone comes as a vaginal insert and as a gel that is inserted high into the vagina. It is administered using a syringe, by a health professional in a hospital or clinic setting. After the dose has been administered you should remain lying down for up to 2 hours as directed by your physician. A second dose of the gel may be administered in 6 hours if the first dose does not produce the desired response.


What are the precautions to be followed?

Before taking dinoprostone,
  • tell your doctor and pharmacist if you are allergic to dinoprostone or any other drugs.
  • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, including vitamins.
  • tell your doctor if you have or have ever had asthma; anemia; a cesarean section or any other uterine surgery; diabetes; high or low blood pressure; placenta previa; a seizure disorder; six or more previous term pregnancies; glaucoma or increased pressure in the eye; cephalopelvic disproportion; previous difficult or traumatic deliveries; unexplained vaginal bleeding; or heart, liver, or kidney disease.

What are possible side effects of this medication ?

Side effects from dinoprostone are not common, but they can occur. Tell your doctor if any of these symptoms are severe or do not go away:
  • upset stomach
  • vomiting
  • diarrhea
  • dizziness
  • flushing of the skin
  • headache
  • fever
If you experience any of the following symptoms, call your doctor immediately:
  • unpleasant vaginal discharge
  • continued fever
  • chills and shivering
  • increase in vaginal bleeding several days after treatment
  • chest pain or tightness
  • skin rash
  • hives
  • difficulty breathing
  • unusual swelling of the face


How to store the medication and dispose it of after its use later?

Dinoprostone gel should be stored in a refrigerator. The inserts should be stored in a freezer. Keep this medication in the container it came in, tightly closed, and out of reach of children.


Drug Category/Class

  • Oxytocics
  • Uterotonics
  • Prostaglandins
  • Genito Urinary System and Sex Hormones
  • Cytochrome P-450 CYP1A2 Inhibitors
  • Cytochrome P-450 CYP1A2 Inducers
  • Prostaglandins
Prescribed For the termination of pregnancy during the second trimester (from the 12th through the 20th gestational week as calculated from the first day of t...
Weight :352.4651
Structure Dinoprostone
Generic Drug Dinoprostone prescribed For the termination of pregnancy during the second trimester (from the 12th through the 20th gestational week as calculated from the first day of t...
Formula

C20H32O5

Dinoprostone has 4 Brands listed


Cerviprime (0.5 mg Syringe)Dinoripe (0.5 mg Syringe)
PG (Vaginal) (Pessary)Primiprost (Vaginal) (Pessary)

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