In uncomplicated falciparum malaria, but it is still not recommended for prophylaxis. Amodiaquine may be effective even in areas with chloroquine-resistant P.falciparum. In combination with artesunate as it is being tried as Artemisinin based Combination Therapy (ACT).
Contraindication: What are the special precautions to be followed?
Under following conditions, use of this medication is inadvisable. Its use should be withhold as it would cause harm to the patient Liver damage, severe GI and haematological diseases, eye impairment. Pregnancy.
Other Precaution to be observed while taking this medication
Injectable form not be used in children below five years. G-6PD deficiency. Peripheral neuropathy, ophthalmic examination required during prolonged therapy.
What are possible side effects of this medication ?
Nausea, vomiting, itching, headache, loss of vision due to retinal damage and corneal deposits. Loss of hearing, rashes, photo allergy, mental disturbances, myopathy and greying of hair.
Drug Category/Class
Antimalarials
Antiprotozoal Agents
Antiparasitic Products, Insecticides and Repellents
Aminoquinolines
Cytochrome P-450 CYP2C8 Inhibitors
Cytochrome P-450 CYP2C8 Inducers
Cytochrome P-450 CYP2C9 Inhibitors
Cytochrome P-450 CYP2C9 Inducers
CYP2D6 Inducers
CYP2D6 Inducers (strong)
Aminoquinolines
Artemisinin and derivatives, combinations
Prescribed
For treatment of acute malarial attacks in non-immune subjects.
